BDE-47, -99, -209 and Their Ternary Mixture Disrupt Glucose and Lipid Metabolism of Hepg2 Cells at Dietary Relevant Concentrations: Mechanistic Insight through Integrated Transcriptomics and Proteomics Analysis

Polybrominated diphenyl ethers (PBDEs) are persistent organic chemicals implied as flame retardants. Humans are mainly exposed to BDE-47, -99, and -209 congeners by diet. PBDEs are metabolic disruptors with the liver as the main target organ. To investigate their mode of action at a human-relevant c...

Descripción completa

Detalles Bibliográficos
Autores principales: Casella, Marialuisa, Lori, Gabriele, Coppola, Lucia, La Rocca, Cinzia, Tait, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697228/
https://www.ncbi.nlm.nih.gov/pubmed/36430946
http://dx.doi.org/10.3390/ijms232214465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697228/
https://www.ncbi.nlm.nih.gov/pubmed/36430946
http://dx.doi.org/10.3390/ijms232214465

Ejemplares similares