Computational Analysis of SAM Analogs as Methyltransferase Inhibitors of nsp16/nsp10 Complex from SARS-CoV-2

Methyltransferases (MTases) enzymes, responsible for RNA capping into severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), are emerging important targets for the design of new anti-SARS-CoV-2 agents. Here, analogs of S-adenosylmethionine (SAM), obtained from the bioisosteric substitution of...

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Detalles Bibliográficos
Autores principales: Balieiro, Alessandra M., Anunciação, Eduarda L. S., Costa, Clauber H. S., Qayed, Wesam S., Silva, José Rogério A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697258/
https://www.ncbi.nlm.nih.gov/pubmed/36430451
http://dx.doi.org/10.3390/ijms232213972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697258/
https://www.ncbi.nlm.nih.gov/pubmed/36430451
http://dx.doi.org/10.3390/ijms232213972

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