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Loss of Runx1 Induces Granulosa Cell Defects and Development of Ovarian Tumors in the Mouse

Genetic alterations of the RUNX1 gene are associated with a variety of malignancies, including female-related cancers. The role of RUNX1 as either a tumor suppressor gene or an oncogene is tissue-dependent and varies based on the cancer type. Both the amplification and deletion of the RUNX1 gene hav...

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Detalles Bibliográficos
Autores principales: Bridges, Kamiya, Yao, Humphrey H.-C., Nicol, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697285/
https://www.ncbi.nlm.nih.gov/pubmed/36430923
http://dx.doi.org/10.3390/ijms232214442