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Loss of Runx1 Induces Granulosa Cell Defects and Development of Ovarian Tumors in the Mouse
Genetic alterations of the RUNX1 gene are associated with a variety of malignancies, including female-related cancers. The role of RUNX1 as either a tumor suppressor gene or an oncogene is tissue-dependent and varies based on the cancer type. Both the amplification and deletion of the RUNX1 gene hav...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697285/ https://www.ncbi.nlm.nih.gov/pubmed/36430923 http://dx.doi.org/10.3390/ijms232214442 |