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Pulmonary Safety Profile of Esc Peptides and Esc-Peptide-Loaded Poly(lactide-co-glycolide) Nanoparticles: A Promising Therapeutic Approach for Local Treatment of Lung Infectious Diseases

In recent years, we have discovered Esc(1-21) and its diastereomer (Esc peptides) as valuable candidates for the treatment of Pseudomonas lung infection, especially in patients with cystic fibrosis (CF). Furthermore, engineered poly(lactide-co-glycolide) (PLGA) nanoparticles (NPs) were revealed to b...

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Detalles Bibliográficos
Autores principales: Cappiello, Floriana, Casciaro, Bruno, Loffredo, Maria Rosa, Puglisi, Elena, Lin, Qiao, Yang, Dandan, Conte, Gemma, d’Angelo, Ivana, Ungaro, Francesca, Ferrera, Loretta, Barbieri, Raffaella, Cresti, Laura, Pini, Alessandro, Di, Yuanpu Peter, Mangoni, Maria Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697339/
https://www.ncbi.nlm.nih.gov/pubmed/36365116
http://dx.doi.org/10.3390/pharmaceutics14112297