Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data

Genetic polymorphisms in cytochrome P450 genes can cause variation in metabolism. Thus, single nucleotide variants significantly impact drug pharmacokinetics, toxicity factors, and efficacy and safety of medicines. The distribution of CYP450 alleles varies drastically across ethnicities, with signif...

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Detalles Bibliográficos
Autores principales: Neyshaburinezhad, Navid, Ghasim, Hengameh, Rouini, Mohammadreza, Daali, Youssef, Ardakani, Yalda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697354/
https://www.ncbi.nlm.nih.gov/pubmed/36579562
http://dx.doi.org/10.3390/jpm12111848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697354/
https://www.ncbi.nlm.nih.gov/pubmed/36579562
http://dx.doi.org/10.3390/jpm12111848

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