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Variations in the Frequencies of Polymorphisms in the CYP450s Genes in Eight Major Ethnicities of Iran: A Review of the Human Data
Genetic polymorphisms in cytochrome P450 genes can cause variation in metabolism. Thus, single nucleotide variants significantly impact drug pharmacokinetics, toxicity factors, and efficacy and safety of medicines. The distribution of CYP450 alleles varies drastically across ethnicities, with signif...
Autores principales: | Neyshaburinezhad, Navid, Ghasim, Hengameh, Rouini, Mohammadreza, Daali, Youssef, Ardakani, Yalda H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697354/ https://www.ncbi.nlm.nih.gov/pubmed/36579562 http://dx.doi.org/10.3390/jpm12111848 |
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