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GADD34 Ablation Exacerbates Retinal Degeneration in P23H RHO Mice

The UPR is sustainably activated in degenerating retinas, leading to translational inhibition via p-eIF2α. Recent findings have demonstrated that ablation of growth arrest and DNA damage-inducible protein 34 (GADD34), a protein phosphatase 1 regulatory subunit permitting translational machinery oper...

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Detalles Bibliográficos
Autores principales:	Saltykova, Irina V., Zhylkibayev, Assylbek, Gorbatyuk, Oleg S., Gorbatyuk, Marina S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697375/ https://www.ncbi.nlm.nih.gov/pubmed/36430227 http://dx.doi.org/10.3390/ijms232213748

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