Cargando…

Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury

In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profile of the compound quinolylnitrone QN23, we have prepared and studied sixteen new, related and easily available quinolylnitrones. As a result, we have identified compounds QN4 and QN15 as promising ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Alonso, José M., Escobar-Peso, Alejandro, Fernández, Israel, Alcázar, Alberto, Marco-Contelles, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697404/
https://www.ncbi.nlm.nih.gov/pubmed/36355534
http://dx.doi.org/10.3390/ph15111363