Cargando…
Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury
In our search for new neuroprotective agents for stroke therapy to improve the pharmacological profile of the compound quinolylnitrone QN23, we have prepared and studied sixteen new, related and easily available quinolylnitrones. As a result, we have identified compounds QN4 and QN15 as promising ca...
Autores principales: | Alonso, José M., Escobar-Peso, Alejandro, Fernández, Israel, Alcázar, Alberto, Marco-Contelles, José |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697404/ https://www.ncbi.nlm.nih.gov/pubmed/36355534 http://dx.doi.org/10.3390/ph15111363 |
Ejemplares similares
-
Neuroprotective and Antioxidant Properties of CholesteroNitrone ChN2 and QuinolylNitrone QN23 in an Experimental Model of Cerebral Ischemia: Involvement of Necrotic and Apoptotic Cell Death
por: Chamorro, Beatriz, et al.
Publicado: (2023) -
Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer’s Disease
por: Alonso, José M., et al.
Publicado: (2021) -
Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke
por: Martínez-Alonso, Emma, et al.
Publicado: (2022) -
QnAs with Nenad Ban
por: Ahmed, Farooq
Publicado: (2022) -
QnAs with Terence Hwa
por: Ahmed, Farooq
Publicado: (2022)