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Topiramate Reprofiling for the Attenuation of Cadmium-Induced Testicular Impairment in Rats: Role of NLRP3 Inflammasome and AMPK/mTOR-Linked Autophagy

Topiramate, a promising drug classically used for the management of neurological disorders including epilepsy and migraine, has demonstrated marked anti-inflammatory and anti-apoptotic actions in murine models of cardiac post-infarction inflammation, wound healing, and gastric/intestinal injury. How...

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Detalles Bibliográficos
Autores principales: Arab, Hany H., Abd El Aal, Hayat A., Alsufyani, Shuruq E., El-Sheikh, Azza A. K., Arafa, El-Shaimaa A., Ashour, Ahmed M., Kabel, Ahmed M., Eid, Ahmed H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697422/
https://www.ncbi.nlm.nih.gov/pubmed/36422532
http://dx.doi.org/10.3390/ph15111402