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In Silico Genome Analysis Reveals the Evolution and Potential Impact of SARS-CoV-2 Omicron Structural Changes on Host Immune Evasion and Antiviral Therapeutics

New variants of SARS-CoV-2 continue to evolve. The novel SARS-CoV-2 variant of concern (VOC) B.1.1.529 (Omicron) was particularly menacing due to the presence of numerous consequential mutations. In this study, we reviewed about 12 million SARS-CoV-2 genomic and associated metadata using extensive b...

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Detalles Bibliográficos
Autores principales: Chauhan, Dhruv, Chakravarty, Nikhil, Jeyachandran, Arjit Vijey, Jayakarunakaran, Akshaya, Sinha, Sanjeev, Mishra, Rakesh, Arumugaswami, Vaithilingaraja, Ramaiah, Arunachalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697451/
https://www.ncbi.nlm.nih.gov/pubmed/36366559
http://dx.doi.org/10.3390/v14112461