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Anti-Cocaine IgA Rather Than IgG Mediates Vaccine Protection from Cocaine Use

In developing a vaccine for fentanyl use disorder, we observed that IgA was the best correlate of vaccine-mediated protection from injected drug challenge, rather than IgG or binding affinity. Recent evidence shows that IgA secreting cells line the blood–brain barrier that capture pathogens and coul...

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Detalles Bibliográficos
Autores principales: Kosten, Thomas R., Haile, Colin N., Domingo, Coreen B., Norton, Elizabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697488/
https://www.ncbi.nlm.nih.gov/pubmed/36365186
http://dx.doi.org/10.3390/pharmaceutics14112368