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Anti-Cocaine IgA Rather Than IgG Mediates Vaccine Protection from Cocaine Use
In developing a vaccine for fentanyl use disorder, we observed that IgA was the best correlate of vaccine-mediated protection from injected drug challenge, rather than IgG or binding affinity. Recent evidence shows that IgA secreting cells line the blood–brain barrier that capture pathogens and coul...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697488/ https://www.ncbi.nlm.nih.gov/pubmed/36365186 http://dx.doi.org/10.3390/pharmaceutics14112368 |