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Bioengineering of Escherichia coli Nissle 1917 for Production and Excretion of Spermidine, a Key Metabolite in Human Health

Microbiota-derived metabolites have biological importance for their host. Spermidine, a metabolite described for its protective effect in age-related diseases, is now studied for its role in the resolution of inflammation and gut homeostasis. Strategies to modulate its production in the gastrointest...

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Detalles Bibliográficos
Autores principales: Caffaratti, Clément, Plazy, Caroline, Cunin, Valérie, Toussaint, Bertrand, Le Gouellec, Audrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697600/
https://www.ncbi.nlm.nih.gov/pubmed/36355144
http://dx.doi.org/10.3390/metabo12111061