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Isoforms of Human MARCH1 Differ in Ability to Restrict Influenza A Viruses Due to Differences in Their N Terminal Cytoplasmic Domain

MARCH1 and MARCH8 are closely related E3 ubiquitin ligases that ubiquitinate an overlapping spectrum of host proteins and restrict replication of certain viruses. While the antiviral activity of MARCH8 has been intensively studied, less is known regarding virus inhibition by MARCH1. Isoforms 1 and 2...

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Detalles Bibliográficos
Autores principales: Villalón-Letelier, Fernando, Farrukee, Rubaiyea, Londrigan, Sarah L., Brooks, Andrew G., Reading, Patrick C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697684/
https://www.ncbi.nlm.nih.gov/pubmed/36423158
http://dx.doi.org/10.3390/v14112549