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Kinetic Features of 3′–5′–Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from Saccharomyces cerevisiae

In yeast Saccharomyces cerevisiae cells, apurinic/apyrimidinic (AP) sites are primarily repaired by base excision repair. Base excision repair is initiated by one of two AP endonucleases: Apn1 or Apn2. AP endonucleases catalyze hydrolytic cleavage of the phosphodiester backbone on the 5′ side of an...

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Detalles Bibliográficos
Autores principales: Kuznetsova, Aleksandra A., Gavrilova, Anastasia A., Ishchenko, Alexander A., Saparbaev, Murat, Fedorova, Olga S., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697762/
https://www.ncbi.nlm.nih.gov/pubmed/36430884
http://dx.doi.org/10.3390/ijms232214404