Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors

A novel series of twenty-five rhodamine-linked benzenesulfonamide derivatives (7a–u and 9a–d) were synthesized and screened for their inhibitory action against four physiologically relevant human (h) carbonic anhydrase (CA) isoforms, namely hCA I, hCA II, hCA IX, and hCA XII. All the synthesized mol...

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Detalles Bibliográficos
Autores principales: Swain, Baijayantimala, Khan, Abrar, Singh, Priti, Marde, Vaibhav S., Angeli, Andrea, Chinchilli, Krishna Kartheek, Yaddanapudi, Venkata Madhavi, Carradori, Simone, Supuran, Claudiu T., Arifuddin, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697818/
https://www.ncbi.nlm.nih.gov/pubmed/36432129
http://dx.doi.org/10.3390/molecules27228028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697818/
https://www.ncbi.nlm.nih.gov/pubmed/36432129
http://dx.doi.org/10.3390/molecules27228028

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