Construction and Evaluation of a Novel Organic Anion Transporter 1/3 CRISPR/Cas9 Double-Knockout Rat Model

Background: Organic anion transporter 1 (OAT1) and OAT3 have an overlapping spectrum of substrates such that one can exert a compensatory effect when the other is dysfunctional. As a result, the knockout of either OAT1 or OAT3 is not reflected in a change in the excretion of organic anionic substrat...

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Detalles Bibliográficos
Autores principales: Gou, Xueyan, Ran, Fenglin, Yang, Jinru, Ma, Yanrong, Wu, Xin’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697873/
https://www.ncbi.nlm.nih.gov/pubmed/36365126
http://dx.doi.org/10.3390/pharmaceutics14112307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697873/
https://www.ncbi.nlm.nih.gov/pubmed/36365126
http://dx.doi.org/10.3390/pharmaceutics14112307

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