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A Pilot Study of A2NTX, a Novel Low-Molecular-Weight Neurotoxin Derived from Subtype A2 for Post-Stroke Lower Limb Spasticity: Comparison with OnabotulinumtoxinA

All the currently used type A botulinum neurotoxins for clinical uses are of subtype A1. We compared the efficacy and safety for the first time head-to-head between a novel botulinum toxin A2NTX prepared from subtype A2 and onabotulinumtoxinA (BOTOX) derived from A1 for post-stroke spasticity. We as...

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Detalles Bibliográficos
Autores principales: Kaji, Ryuji, Miyashiro, Ai, Sato, Nori, Furumoto, Taiki, Takeuchi, Toshiaki, Miyamoto, Ryosuke, Kohda, Tomoko, Izumi, Yuishin, Kozaki, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697926/
https://www.ncbi.nlm.nih.gov/pubmed/36355989
http://dx.doi.org/10.3390/toxins14110739