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Sea Cucumber Saponins Derivatives Alleviate Hepatic Lipid Accumulation Effectively in Fatty Acids-Induced HepG2 Cells and Orotic Acid-Induced Rats

The sulfated echinoside A (EA) and holothurin A (HA) are two prominent saponins in sea cucumber with high hemolytic activity but also superior lipid-lowering activity. Deglycosylated derivatives EA2 and HA2 exhibit low hemolysis compared to EA and HA, but their efficacies on lipid metabolism regulat...

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Detalles Bibliográficos
Autores principales: Li, Xiaoyue, Zeng, Beibei, Wen, Lu, Zhao, Yingcai, Li, Zhaojie, Xue, Changhu, Zhang, Tiantian, Wang, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697935/
https://www.ncbi.nlm.nih.gov/pubmed/36355027
http://dx.doi.org/10.3390/md20110703