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HMGCS2 Mediation of Ketone Levels Affects Sorafenib Treatment Efficacy in Liver Cancer Cells

Primary liver cancer is the fifth leading death of cancers in men, and hepatocellular carcinoma (HCC) accounts for approximately 90% of all primary liver cancer cases. Sorafenib is a first-line drug for advanced-stage HCC patients. Sorafenib is a multi-target kinase inhibitor that blocks tumor cell...

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Detalles Bibliográficos
Autores principales: Suk, Fat-Moon, Wu, Chien-Ying, Chiu, Wan-Chun, Chien, Chia-Ying, Chen, Tzu-Lang, Liao, Yi-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9697984/
https://www.ncbi.nlm.nih.gov/pubmed/36432116
http://dx.doi.org/10.3390/molecules27228015