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Insights into Antimalarial Activity of N-Phenyl-Substituted Cinnamanilides

Due to the urgent need of innovation in the antimalarial therapeutic arsenal, a series of thirty-seven ring-substituted N-arylcinnamanilides prepared by microwave-assisted synthesis were subjected to primary screening against the chloroquine-sensitive strain of P. falciparum 3D7/MRA-102. The lipophi...

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Detalles Bibliográficos
Autores principales: Kos, Jiri, Degotte, Gilles, Pindjakova, Dominika, Strharsky, Tomas, Jankech, Timotej, Gonec, Tomas, Francotte, Pierre, Frederich, Michel, Jampilek, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698057/
https://www.ncbi.nlm.nih.gov/pubmed/36431900
http://dx.doi.org/10.3390/molecules27227799