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Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans

On-tissue enzymatic digestion is a prerequisite for MALDI mass spectrometry imaging (MSI) and spatialomic analysis of tissue proteins and their N-glycan conjugates. Despite the more widely accepted importance of N-glycans as diagnostic and prognostic biomarkers of many diseases and their potential a...

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Detalles Bibliográficos
Autores principales: Fülöp, Annabelle, Marsching, Christian, Barka, Frederik, Ucal, Yasemin, Pfänder, Pauline, Opitz, Christiane A., Barka, Günes, Hopf, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698097/
https://www.ncbi.nlm.nih.gov/pubmed/36355528
http://dx.doi.org/10.3390/ph15111356