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Drug Combination Studies of the Dipeptide Nitrile CD24 with Curcumin: A New Strategy to Synergistically Inhibit Rhodesain of Trypanosoma brucei rhodesiense

Rhodesain is a cysteine protease that is crucial for the life cycle of Trypanosoma brucei rhodesiense, a parasite causing the lethal form of Human African Trypanosomiasis. CD24 is a recently developed synthetic inhibitor of rhodesain, characterized by a nanomolar affinity towards the trypanosomal pr...

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Detalles Bibliográficos
Autores principales:	Di Chio, Carla, Previti, Santo, De Luca, Fabiola, Bogacz, Marta, Zimmer, Collin, Wagner, Annika, Schirmeister, Tanja, Zappalà, Maria, Ettari, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698140/ https://www.ncbi.nlm.nih.gov/pubmed/36430948 http://dx.doi.org/10.3390/ijms232214470

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