BAM15 Relieves Neurodegeneration in Aged Caenorhabditis elegans and Extends Lifespan

BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneration in the nematode Caenorhabditis elegans during ag...

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Detalles Bibliográficos
Autores principales: Cho, Injeong, Song, Hyun-Ok, Ji, Ha Eun, Yang, Sungtae, Cho, Jeong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698188/
https://www.ncbi.nlm.nih.gov/pubmed/36422268
http://dx.doi.org/10.3390/metabo12111129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698188/
https://www.ncbi.nlm.nih.gov/pubmed/36422268
http://dx.doi.org/10.3390/metabo12111129

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