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BAM15 Relieves Neurodegeneration in Aged Caenorhabditis elegans and Extends Lifespan
BAM15 was recently screened as a protonophore uncoupler specifically for the mitochondrial membrane but not the plasma membrane. It is equally as potent as FCCP, but less toxic. Previously, mitochondrial uncoupling via DNP alleviates neurodegeneration in the nematode Caenorhabditis elegans during ag...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698188/ https://www.ncbi.nlm.nih.gov/pubmed/36422268 http://dx.doi.org/10.3390/metabo12111129 |