Rational Design of a Peptidomimetic Inhibitor of Gelsolin Amyloid Aggregation

Gelsolin amyloidosis (AGel) is characterized by multiple systemic and ophthalmic features resulting from pathological tissue deposition of the gelsolin (GSN) protein. To date, no cure is available for the treatment of any form of AGel. More than ten single-point substitutions in the GSN gene are res...

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Detalles Bibliográficos
Autores principales: Bollati, Michela, Peqini, Kaliroi, Barone, Luigi, Natale, Carmina, Beeg, Marten, Gobbi, Marco, Diomede, Luisa, Trucchi, Michelangelo, de Rosa, Matteo, Pellegrino, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698219/
https://www.ncbi.nlm.nih.gov/pubmed/36430461
http://dx.doi.org/10.3390/ijms232213973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698219/
https://www.ncbi.nlm.nih.gov/pubmed/36430461
http://dx.doi.org/10.3390/ijms232213973

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