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Involvement of the p38 MAPK-NLRC4-Caspase-1 Pathway in Ionizing Radiation-Enhanced Macrophage IL-1β Production

Macrophages are abundant immune cells in the tumor microenvironment and are crucial in regulating tumor malignancy. We previously reported that ionizing radiation (IR) increases the production of interleukin (IL)-1β in lipopolysaccharide (LPS)-treated macrophages, contributing to the malignancy of c...

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Detalles Bibliográficos
Autores principales: Baik, Ji Sue, Seo, You Na, Lee, Young-Choon, Yi, Joo Mi, Rhee, Man Hee, Park, Moon-Taek, Kim, Sung Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698243/
https://www.ncbi.nlm.nih.gov/pubmed/36430236
http://dx.doi.org/10.3390/ijms232213757