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Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis

Targeted molecular radiation therapy is a promising emerging treatment modality in oncology, and peptide synthesis may shorten the time to reach the clinical stage. In this study, we have explored Chemo-Enzymatic Peptide Synthesis, or CEPS, as a new means of producing a therapeutic HER2 targeted Aff...

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Detalles Bibliográficos
Autores principales: Liu, Yongsheng, Güler, Rezan, Liao, Yunqi, Vorobyeva, Anzhelika, Widmark, Olof, Meuleman, Theodorus J., Koijen, Anna, van den Bos, Leendert J., Naasz, Robert, Bodenko, Vitalina, Orlova, Anna, Ekblad, Caroline, Tolmachev, Vladimir, Frejd, Fredrik Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698269/
https://www.ncbi.nlm.nih.gov/pubmed/36432709
http://dx.doi.org/10.3390/pharmaceutics14112519