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TGF-β from the Porcine Intestinal Cell Line IPEC-J2 Induced by Porcine Circovirus 2 Increases the Frequency of Treg Cells via the Activation of ERK (in CD4(+) T Cells) and NF-κB (in IPEC-J2)

Porcine circovirus 2 (PCV2) causes immunosuppression. Piglets infected with PCV2 can develop enteritis. Given that the gut is the largest immune organ, however, the response of the gut’s immune system to PCV2 is still unclear. Here, IPEC-J2 cells with different treatments were co-cultured with PBMC...

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Detalles Bibliográficos
Autores principales: Liu, Xuewei, Wang, Yang, Han, Cheng, Li, Qiuming, Hou, Xiaolin, Song, Qinye, Zhou, Shuanghai, Li, Huanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698303/
https://www.ncbi.nlm.nih.gov/pubmed/36366564
http://dx.doi.org/10.3390/v14112466