Developing 3D Organoid Raft Cultures from Patient-Derived Xenografts as Rapid Models to Screen Efficacy of Experimental Therapeutics

Reliable preclinical models are needed for screening new cancer drugs. Thus, we developed an improved 3D tumor organoid model termed “organoid raft cultures” (ORCs). Development of ORCs involved culturing tumors ex vivo on collagen beds (boats) with grid supports to maintain their morphological stru...

Descripción completa

Detalles Bibliográficos
Autores principales: Bajpai, Prachi, Banerjee, Nilam Sanjib, Moore, Dianne W., Kim, Hyung-Gyoon, Afaq, Farrukh, Contreras, Carlo M., Heslin, Martin J., Reddy, Vishnu B., Peter, Shajan, Varambally, Sooryanarayana, Al Diffalha, Sameer, Manne, Upender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698332/
https://www.ncbi.nlm.nih.gov/pubmed/36430867
http://dx.doi.org/10.3390/ijms232214392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698332/
https://www.ncbi.nlm.nih.gov/pubmed/36430867
http://dx.doi.org/10.3390/ijms232214392

Ejemplares similares