Cargando…

PI(4,5)P(2) diffuses freely in the plasma membrane even within high-density effector protein complexes

The lipid phosphatidyl-D-myo-inositol-4,5-bisphosphate [PI(4,5)P(2)] is a master regulator of plasma membrane (PM) function. Its effector proteins regulate transport, signaling, and cytoskeletal processes that define PM structure and function. How a single type of lipid regulates so many parallel pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacheco, Jonathan, Cassidy, Anna C., Zewe, James P., Wills, Rachel C., Hammond, Gerald R.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698391/
https://www.ncbi.nlm.nih.gov/pubmed/36416724
http://dx.doi.org/10.1083/jcb.202204099