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Depletion of Na(+)/H(+) Exchanger Isoform 1 Increases the Host Cell Resistance to Trypanosoma cruzi Invasion
Na(+)/H(+) exchanger isoform 1 (NHE1), a member of a large family of integral membrane proteins, plays a role in regulating the cortical actin cytoskeleton. Trypanosoma cruzi, the agent of Chagas disease, depends on F-actin rearrangement and lysosome mobilization to invade host cells. To determine t...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698427/ https://www.ncbi.nlm.nih.gov/pubmed/36365045 http://dx.doi.org/10.3390/pathogens11111294 |