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Depletion of Na(+)/H(+) Exchanger Isoform 1 Increases the Host Cell Resistance to Trypanosoma cruzi Invasion

Na(+)/H(+) exchanger isoform 1 (NHE1), a member of a large family of integral membrane proteins, plays a role in regulating the cortical actin cytoskeleton. Trypanosoma cruzi, the agent of Chagas disease, depends on F-actin rearrangement and lysosome mobilization to invade host cells. To determine t...

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Detalles Bibliográficos
Autores principales: Rodrigues, João Paulo Ferreira, Loch, Leonardo, Onofre, Thiago Souza, Yoshida, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698427/
https://www.ncbi.nlm.nih.gov/pubmed/36365045
http://dx.doi.org/10.3390/pathogens11111294