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Identification of Dihydrolipoamide Dehydrogenase as Potential Target of Vemurafenib-Resistant Melanoma Cells

Background: Despite recent improvements in therapy, the five-year survival rate for patients with advanced melanoma is poor, mainly due to the development of drug resistance. The aim of the present study was to investigate the mechanisms underlying this phenomenon, applying proteomics and structural...

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Detalles Bibliográficos
Autores principales: Tabolacci, Claudio, Giordano, Deborah, Rossi, Stefania, Cordella, Martina, D’Arcangelo, Daniela, Moschella, Federica, D’Atri, Stefania, Biffoni, Mauro, Facchiano, Angelo, Facchiano, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698468/
https://www.ncbi.nlm.nih.gov/pubmed/36431901
http://dx.doi.org/10.3390/molecules27227800