Cargando…

Cross-Reactive Fc-Fused Single-Domain Antibodies to Hemagglutinin Stem Region Protect Mice from Group 1 Influenza a Virus Infection

The continued evolution of influenza viruses reduces the effectiveness of vaccination and antiviral drugs. The identification of novel and universal agents for influenza prophylaxis and treatment is an urgent need. We have previously described two potent single-domain antibodies (VHH), G2.3 and H1.2...

Descripción completa

Detalles Bibliográficos
Autores principales: Voronina, Daria V., Shcheblyakov, Dmitry V., Favorskaya, Irina A., Esmagambetov, Ilias B., Dzharullaeva, Alina S., Tukhvatulin, Amir I., Zubkova, Olga V., Popova, Olga, Kan, Vladislav Y., Bandelyuk, Alina S., Shmarov, Maxim M., Logunov, Denis Y., Naroditskiy, Boris S., Gintsburg, Aleksandr L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698552/
https://www.ncbi.nlm.nih.gov/pubmed/36366583
http://dx.doi.org/10.3390/v14112485