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Cross-Reactive Fc-Fused Single-Domain Antibodies to Hemagglutinin Stem Region Protect Mice from Group 1 Influenza a Virus Infection
The continued evolution of influenza viruses reduces the effectiveness of vaccination and antiviral drugs. The identification of novel and universal agents for influenza prophylaxis and treatment is an urgent need. We have previously described two potent single-domain antibodies (VHH), G2.3 and H1.2...
Autores principales: | Voronina, Daria V., Shcheblyakov, Dmitry V., Favorskaya, Irina A., Esmagambetov, Ilias B., Dzharullaeva, Alina S., Tukhvatulin, Amir I., Zubkova, Olga V., Popova, Olga, Kan, Vladislav Y., Bandelyuk, Alina S., Shmarov, Maxim M., Logunov, Denis Y., Naroditskiy, Boris S., Gintsburg, Aleksandr L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698552/ https://www.ncbi.nlm.nih.gov/pubmed/36366583 http://dx.doi.org/10.3390/v14112485 |
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