In Silico Analysis of Tetrodotoxin Binding in Voltage-Gated Sodium Ion Channels from Toxin-Resistant Animal Lineages

Multiple animal species have evolved resistance to the neurotoxin tetrodotoxin (TTX) through changes in voltage-gated sodium ion channels (VGSCs). Amino acid substitutions in TTX-resistant lineages appear to be positionally convergent with changes in homologous residues associated with reductions in...

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Detalles Bibliográficos
Autores principales: Geffeney, Shana L., Cordingley, Jennie Ann, Mitchell, Kenyon, Hanifin, Charles T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698786/
https://www.ncbi.nlm.nih.gov/pubmed/36422001
http://dx.doi.org/10.3390/md20110723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698786/
https://www.ncbi.nlm.nih.gov/pubmed/36422001
http://dx.doi.org/10.3390/md20110723

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