Formulation Characterization and Pharmacokinetic Evaluation of Amorphous Solid Dispersions of Dasatinib

The aim of this study was to improve the physicochemical properties and oral bioavailability of dasatinib (DST) by the amorphous solid dispersion (ASD) approach using cellulose acetate butyrate (CAB) as a carrier. Various formulations of ASD (DST:CAB 1:1 to 1:5) were prepared by the solvent evaporat...

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Detalles Bibliográficos
Autores principales: Dharani, Sathish, Mohamed, Eman M., Khuroo, Tahir, Rahman, Ziyaur, Khan, Mansoor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698804/
https://www.ncbi.nlm.nih.gov/pubmed/36432641
http://dx.doi.org/10.3390/pharmaceutics14112450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698804/
https://www.ncbi.nlm.nih.gov/pubmed/36432641
http://dx.doi.org/10.3390/pharmaceutics14112450

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