Structural Modelling Prediction of Recombinant Plasmodium falciparum K13-F446I and K13-C580Y Gene by AlphaFold Method and Heterologous Expression in Spodoptera frugiperda 9 Cells

P. falciparum Kelch 13 (Pfk13) is an essential protein that contains BTB and Kelch-repeat propeller domains (KRPD), which was predicted to bind substrate during ubiquitin-dependent degradation pathway. However, the function of Pfk13 and the structural alterations associated with artemisinin resistan...

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Detalles Bibliográficos
Autores principales: Yan, He, Feng, Jun, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698840/
https://www.ncbi.nlm.nih.gov/pubmed/36365022
http://dx.doi.org/10.3390/pathogens11111271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698840/
https://www.ncbi.nlm.nih.gov/pubmed/36365022
http://dx.doi.org/10.3390/pathogens11111271

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