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Hepatocyte DAX1 Deletion Exacerbates Inflammatory Liver Injury by Inducing the Recruitment of CD4(+) and CD8(+) T Cells through NF-κB p65 Signaling Pathway in Mice

Fulminant hepatitis is characterized by rapid and massive immune-mediated liver injury. Dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1; NR0B1) represses the transcription of various genes. Here, we determine whether DAX1 serves as a regul...

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Detalles Bibliográficos
Autores principales: Yun, Hyo-Jeong, Suh, Young-Joo, Kim, Yu-Bin, Kang, Eun-Jung, Choi, Jung Hyeon, Choi, Young-Keun, Lee, In-Bok, Choi, Dong-Hee, Seo, Yun Jeong, Noh, Jung-Ran, Choi, Hueng-Sik, Kim, Yong-Hoon, Lee, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698938/
https://www.ncbi.nlm.nih.gov/pubmed/36430486
http://dx.doi.org/10.3390/ijms232214009