Study of Hypoglycemic Activity of Novel 9-N-alkyltetrahydroberberine Derivatives

Novel 9-N-alkyltetrahydroberberine derivatives were synthesized, among which, based on the results of OGTT, one compound containing the longest aliphatic substituent was selected for study in mice C57BL/6(Ay), which demonstrate obesity, impaired glucose tolerance, and concomitant liver non-alcoholic...

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Detalles Bibliográficos
Autores principales: Khvostov, Mikhail V., Gladkova, Elizaveta D., Borisov, Sergey A., Fedotova, Marina S., Zhukova, Nataliya A., Marenina, Mariya K., Meshkova, Yuliya V., Luzina, Olga A., Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698964/
https://www.ncbi.nlm.nih.gov/pubmed/36430664
http://dx.doi.org/10.3390/ijms232214186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698964/
https://www.ncbi.nlm.nih.gov/pubmed/36430664
http://dx.doi.org/10.3390/ijms232214186

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