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Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis

Hepatocellular carcinoma (HCC) is a major subtype of primary liver cancer with a high mortality rate. Pyroptosis and autophagy are crucial processes in the pathophysiology of HCC. Searching for efficient drugs targeting pyroptosis and autophagy with lower toxicity is useful for HCC treatment. Mallot...

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Detalles Bibliográficos
Autores principales: Dai, Xiaoyong, Sun, Fen, Deng, Kexin, Lin, Gaoyang, Yin, Wenjing, Chen, Huaqing, Yang, Dongye, Liu, Kewei, Zhang, Yubo, Huang, Laiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9698996/
https://www.ncbi.nlm.nih.gov/pubmed/36430694
http://dx.doi.org/10.3390/ijms232214217