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Bioinformatic Analysis of Kynurenine Pathway Enzymes and Their Relationship with Glioma Hallmarks

Indoleamine dioxygenase (IDO), a rate limiting enzyme of the tryptophan catabolism through the kynurenine pathway (KP), has been related with a lower survival and a poor patient prognosis on several solid tumors, including gliomas. However, the use of IDO inhibitors as a therapeutic strategy for tum...

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Detalles Bibliográficos
Autores principales: Vázquez Cervantes, Gustavo Ignacio, Navarro Cossio, Javier Ángel, Pérez de la Cruz, Gonzalo, Salazar, Aleli, Pérez de la Cruz, Verónica, Pineda, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699055/
https://www.ncbi.nlm.nih.gov/pubmed/36355137
http://dx.doi.org/10.3390/metabo12111054