New TMA (4,6,4′-Trimethyl angelicin) Analogues as Anti-Inflammatory Agents in the Treatment of Cystic Fibrosis Lung Disease

A series of new-generation TMA (4,6,4′-trimethyl angelicin) analogues was projected and synthetized in order to ameliorate anti-inflammatory activity, with reduced or absent toxicity. Since the NF-κB transcription factor (TF) plays a critical role in the expression of IL-8 (Interluekin 8), a typical...

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Detalles Bibliográficos
Autores principales: Tupini, Chiara, Chilin, Adriana, Rossi, Alice, De Fino, Ida, Bragonzi, Alessandra, D’Aversa, Elisabetta, Cosenza, Lucia Carmela, Vaccarin, Christian, Sacchetti, Gianni, Borgatti, Monica, Tamanini, Anna, Dechecchi, Maria Cristina, Sanvito, Francesca, Gambari, Roberto, Cabrini, Giulio, Lampronti, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699093/
https://www.ncbi.nlm.nih.gov/pubmed/36430961
http://dx.doi.org/10.3390/ijms232214483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699093/
https://www.ncbi.nlm.nih.gov/pubmed/36430961
http://dx.doi.org/10.3390/ijms232214483

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