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Dynamic Change of R-Loop Implicates in the Regulation of Zygotic Genome Activation in Mouse

In mice, zygotic genome activation (ZGA) occurs in two steps: minor ZGA at the one–cell stage and major ZGA at the two–cell stage. Regarding the regulation of gene transcription, minor ZGA is known to have unique features, including a transcriptionally permissive state of chromatin and insufficient...

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Detalles Bibliográficos
Autores principales: Lee, Hyeonji, You, Seong-Yeob, Han, Dong Wook, La, Hyeonwoo, Park, Chanhyeok, Yoo, Seonho, Kang, Kiye, Kang, Min-Hee, Choi, Youngsok, Hong, Kwonho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699122/
https://www.ncbi.nlm.nih.gov/pubmed/36430821
http://dx.doi.org/10.3390/ijms232214345