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Dynamic Change of R-Loop Implicates in the Regulation of Zygotic Genome Activation in Mouse
In mice, zygotic genome activation (ZGA) occurs in two steps: minor ZGA at the one–cell stage and major ZGA at the two–cell stage. Regarding the regulation of gene transcription, minor ZGA is known to have unique features, including a transcriptionally permissive state of chromatin and insufficient...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699122/ https://www.ncbi.nlm.nih.gov/pubmed/36430821 http://dx.doi.org/10.3390/ijms232214345 |