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DRPreter: Interpretable Anticancer Drug Response Prediction Using Knowledge-Guided Graph Neural Networks and Transformer

Some of the recent studies on drug sensitivity prediction have applied graph neural networks to leverage prior knowledge on the drug structure or gene network, and other studies have focused on the interpretability of the model to delineate the mechanism governing the drug response. However, it is c...

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Detalles Bibliográficos
Autores principales: Shin, Jihye, Piao, Yinhua, Bang, Dongmin, Kim, Sun, Jo, Kyuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699175/
https://www.ncbi.nlm.nih.gov/pubmed/36430395
http://dx.doi.org/10.3390/ijms232213919