Dehydroepiandrosterone Cocrystals with Improved Solubility and Bioavailability

Dehydroepiandrosterone (DHEA) is an FDA-approved food supplement used as an assisted reproductive sex hormone. The bioavailability is severely limited by its poor solubility (23 µg/mL). Herein, we aimed to modulate its solubility through cocrystallization. Eight cocrystals of DHEA with pyrocatechol...

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Detalles Bibliográficos
Autores principales: Jiang, Yihua, Cheng, Yinxiang, Xia, Mengyuan, Zhang, Bingrui, Ding, Qiaoce, Lu, Liye, Wang, Jian-Rong, Mei, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699216/
https://www.ncbi.nlm.nih.gov/pubmed/36432669
http://dx.doi.org/10.3390/pharmaceutics14112478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699216/
https://www.ncbi.nlm.nih.gov/pubmed/36432669
http://dx.doi.org/10.3390/pharmaceutics14112478

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