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Dehydroepiandrosterone Cocrystals with Improved Solubility and Bioavailability

Dehydroepiandrosterone (DHEA) is an FDA-approved food supplement used as an assisted reproductive sex hormone. The bioavailability is severely limited by its poor solubility (23 µg/mL). Herein, we aimed to modulate its solubility through cocrystallization. Eight cocrystals of DHEA with pyrocatechol...

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Detalles Bibliográficos
Autores principales:	Jiang, Yihua, Cheng, Yinxiang, Xia, Mengyuan, Zhang, Bingrui, Ding, Qiaoce, Lu, Liye, Wang, Jian-Rong, Mei, Xuefeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699216/ https://www.ncbi.nlm.nih.gov/pubmed/36432669 http://dx.doi.org/10.3390/pharmaceutics14112478

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