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Continuous-Flow Synthesis of Arylthio-Cyclopropyl Carbonyl Compounds

The straightforward, continuous-flow synthesis of cyclopropyl carbaldehydes and ketones has been developed starting from 2-hydroxycyclobutanones and aryl thiols. This acid-catalyzed mediated procedure allows access to the multigram and easily scalable synthesis of cyclopropyl adducts under mild cond...

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Detalles Bibliográficos
Autores principales: Moi, Davide, Cabua, Maria Chiara, Velichko, Viktoria, Cocco, Andrea, Chiappone, Annalisa, Mocci, Rita, Porcu, Stefania, Piras, Monica, Bianco, Stefano, Pesciaioli, Fabio, Secci, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699303/
https://www.ncbi.nlm.nih.gov/pubmed/36432044
http://dx.doi.org/10.3390/molecules27227943